Researchers from MIT and the University of California have developed nanoparticles (NPs) that are biodegradable, break down readily in the body once the drug payload has been delivered and are easily excreted by the kidneys.
In-vivo tests have so far shown that the NPs can deliver the anti-cancer drug doxorubicin into tumors and can then degrade and be excreted in 1-4 weeks, showing no indications of toxicity.
These tests show a promising future for this kind of drug delivery system. Real headway will be made once it is proven that in the long-term as well as short-term the NP treatment displays no toxicity in the body. – CT
Paper: Nature Materials