A collaborative effort between researchers at the university of Michigan and Nanobio Corporation have lead to the development of a new lotion that inhibits bacterial growth, when applied to second degree burns.
Sites of extensive skin damage are sites that become easily infected with bacterium as the bodies first defensive wall to microbes has been destroyed. For this reason the lotion is a welcome addition to burn treatments to combat the problem of bacterial infection of the burn site.
This new lotion has overcome the shortcommings of other creams as it can penetrate the skin and kill sub-surface bacterium.
The technique was discovered by a team from the University of Michigan Medical School by Mark Hemilla M.D. a surgeon.
The lotion contains soybean oil, alcohol, water and detergents. The constituents are emulsified into droplets with a less than 400nm diameter.
This technique was shown to reduce bacterial growth 100-fold in animal tests, compared to those with no treatment or a placebo. It would seem that the lotion also shows bacteriocidal, virocidal and fungicidal effects from previous research.
The mechanism of function seems to indicate the inhibition of two cytokines that are important for signalling post- burn. This correlates to a reduction in inflammation allowing limitation of damage in the post-burn period. As it is well known that excessive inflammtion after damage to tissue can cause more damage then good by creating further tissue damage.
The lotion thus has a duel action ideal for the treatment of burns. In the first instance reucing inflammtion whillst at the same time reducing bacterial growth, reducing the likelihood of bacterial infection post-burn. – CT